| Authors |
Ermolaeva Aleksandra Ionashevna, Doctor of medical sciences, assosciate professor, head of sub-department of neurology and neurosurgery, Medical institute, Penza State University (40 Krasnaya street, Penza, Russia), neurology-mipgy@yandex.ru
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| Abstract |
Background. The purpose of the article is to study the clinical aspects of the course of acute cerebral blood circulation disturbances of ischemic type and the indications of the stress-realizing system in case of diabetes mellitus type II.
Materials and methods. One hundred and two patients with ischemic stroke and diabetes mellitus type II and fifty patients of the control group with ischemic stroke and without diabetes mellitus type II were examined. The level of consciousness disorder was estimated by the Glasgow scale, the evidence of nephrological deficiency was estimated by the Scandinavian scale. Twenty five patients were examined for the stress-realizing system hormones (TSH, T4, T3, cortisol).
Results. The patients with diabetes mellitus had more serious clinical performance of ischemic stroke: the evident disorder of consciousness happened more often, the Glasgow coma scale total score in the study group was lower than in the control group. The neurological status of the study group patients had evident focal neurological signs. Mortality was 2,5 times higher than in the control group. According to the correlation analysis the increase of the glycaemic level is accompanied by the decrease of the Glasgow coma scale total score, which denotes more critical conditions of the patients. The increase of diabetes mellitus type II duration is accompanied by the decrease of the Scandinavian scale average score, wich denotes high evidence of nephrological deficiency. During the investigation of the stress-realizing system hormones, T3 decrease during the first days of ischemic stroke in case of diabetes mellitus was less evident than in the control group. The value of cortisol during the first day in the study group was higher than in the control group. Based on the results of the research conducted we can come to the conclusion, that the reaction of the stress-realizing system hormones in the presence of diabetes mellitus has its special aspects and we should consider them in diagnostics
and treatment.
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